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Age-dependent acquisition of pathogenicity by SARS-CoV-2 Omicron BA.5

Date
Friday, September 22, 2023 - 4:00 AM
Description
Pathology studies of SARS-CoV-2 Omicron variants of concern (VOC) are challenged by the lack of pathogenic animal models. While Omicron BA.1 and BA.2 replicate in K18-hACE2 transgenic mice, they cause minimal to negligible morbidity and mortality